Abstract
Abstract: Premature rupture of membranes (PROM) has the potential effect to cause complications such as premature infants, neonatal sepsis, and intrauterine infection (chorioamnionitis). Some inflammatory markers have been investigated to detect PROM at their early stage and prevent the complications. Platelet lymphocyte ratio (PLR) and leukocytes are a simple, affordable inflammatory marker, and have been used to predict a variety of inflammatory conditions. This study aims to see the relationship between PLR and leukocytes with APGAR Score in the case of PROM. This study was an analytic observational study with a retrospective cross sectional design. Data from 80 samples showed PLR and leucocytes had no significant effect on APGAR value (p> 0.05). Keywords: Platelet Lymphocyte Ratio, Premature rupture of membranes, APGAR score
Highlights
Premature Rupture of Membrane’s (PROM) incidence ranges from 10% to 30% of all births
The incidence of chorioamnionitis infection increases from 6-10% to 40% if PROM occurs> 24 hours
Various factors play a role in the pathogenesis of PROM / Premature Rupture of Membrane (PPROM) occurrence; especially the inflammatory factor plays an important role in the occurrence of membrane rupture.[3]
Summary
Premature Rupture of Membrane’s (PROM) incidence ranges from 10% to 30% of all births. PROMs are grouped into two based on the timing of occurrence, PROM or Premature Rupture of Membrane (PROM) and preterm PROM or Preterm Premature Rupture of Membrane (PPROM). PROM has the potential to cause complications of premature infants, neonatal sepsis and the risk of intrauterine infection (chorioamnionitis).[1,2]. The incidence of PROM in Ulin General Hospital occurred as 126 cases in 2016. The incidence of chorioamnionitis infection increases from 6-10% to 40% if PROM occurs> 24 hours. While the risk of neonatal infection increased to 2x fold.[23]. Various factors play a role in the pathogenesis of PROM / PPROM occurrence; especially the inflammatory factor plays an important role in the occurrence of membrane rupture.[3]
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