Abstract
Cats given dimethylsulfoxide intravenously exhale 3% of the administered dose as the volatile metabolite dimethylsulfide within 5 hours. The rate of respiratory excretion of dimethylsulfide appears to be limited by the rate of its metabolic production, rather than by respiratory factors. The liver does not appear to be a major site of the reduction of dimethylsulfoxide to dimethylsulfide because hepatectomy does not significantly affect the rate of dimethylsulfide excretion. Dimethylsulfoxide is reduced in vitro to dimethylsulfide by cysteine and glutathione, suggesting a nonenzymatic conversion.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
