RAS, MYC, and Sensitivity to Tumor Necrosis Factor-α–Related Apoptosis-Inducing Ligand–Induced Apoptosis

Abstract

To the Editor: Considerable excitement has surrounded the observation that the cytokine tumor necrosis factor-α–related apoptosis-inducing ligand (TRAIL) induces apoptosis in many tumor cell types but has little or no effect on nontransformed cells. Two recent articles attempt to elucidate the