Abstract
Rare Association of Bilateral Fracture of the Femoral Neck and Slipped Capital Femoral Epiphysis in Osteopetrosis Patient
Highlights
Osteopetrosis, called marble bone disease, Albers-Schonberg disease belongs to the group of bone dysplasia, comprising a clinically and genetically heterogeneous group of conditions that share the hallmark of increased bone density on radiograph
We report a case of Osteopetrosis (ADO) with bilateral femoral neck fractures (Salter and Harris II) plus slipped capital femoral epiphysis treated in first round conservatively and surgically as-yet-unreported
Et al, [9] indicate four factors have been postulated in the pathogenesis of slipped capital femoral epiphysis: Increased height of the epiphysis, changes in the inclination angle of the physis, abnormal loading of the growth plate, and insufficiency of the components of the physeal cartilage
Summary
Osteopetrosis, called marble bone disease, Albers-Schonberg disease belongs to the group of bone dysplasia, comprising a clinically and genetically heterogeneous group of conditions that share the hallmark of increased bone density on radiograph. The increase in bone density results from abnormalities in osteoclast differentiation or function and persistence of calcified chondroid material, causing the bone to be dense and brittle [1]. Albers-Schonberg was the first to describe in 1904 in a 26-yearold patient [1,2]. The medullary cavity is filled with endochondral new bone, with little space remaining for hematopoietic cells. This abnormality contributes to the brittleness of bone in osteopetrosis
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