Abstract

200 phrenics showed a significantly greater than mean difference (1.83 1?1 1.85 versus 0.12 k 2.08 cm*, p = .02). No other significant differences emerged, due in part to the high degree of variance in the measures from slice A, as it is located near the poles of the temporal lobe. These results suggests that temporal lobe anatomical differences between schizophrenics and controls can be identified using MRI, that these structures differ in right-left symmetry, and that such asymmetries may be related to the neuropathology of schizophrenia. Further, this study is consistent with previous findings of abnormalities in the structure and function of the temporal lobe in schizophrenia. Further structural analyses will be presented.

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