Abstract
Global elimination of hepatitis B virus (HBV) requires scale-up of testing and treatment services in low-income and middle-income countries (LMICs). Following the screening for hepatitis B surface antigen (HBsAg), quantification of serum HBV DNA is invariably required to identify a subset of HBV-infected individuals who should immediately start antiviral therapy. Anti-HBV treatment is recommended for patients with chronic HBV infection (CHB) who have high HBV DNA levels (≥2000 or ≥20,000 IU/mL) in the presence of liver fibrosis or inflamation.
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