Abstract
The excessive use or abuse of pesticides and veterinary drugs leads to residues in food, which can threaten human health. Therefore, there is an extremely urgent need for multi-analyte analysis techniques for the detection of pesticide and veterinary drug residues, which can be applied as screening techniques for food safety monitoring and detection. Recent developments related to rapid multi-residue detection methods for pesticide and veterinary drug residues are reviewed herein. Methods based on different recognition elements or the inherent characteristics of pesticides and veterinary drugs are described in detail. The preparation and application of three broadly specific recognition elements—antibodies, aptamers, and molecular imprinted polymers—are summarized. Furthermore, enzymatic inhibition-based sensors, near-infrared spectroscopy, and SERS spectroscopy based on the inherent characteristics are also discussed. The aim of this review is to provide a useful reference for the further development of rapid multi-analyte analysis of pesticide and veterinary drug residues.
Highlights
Pesticides and veterinary drugs are indispensable for increasing food production, as well as improving animal breeding and aquaculture [1]
Antibodies have long been the most common recognition elements used in rapid detection Antibodies have long approaches, been the most common recognition elements used in rapid methods
A recombinant antibody variable fragment with broad specificity for organophosphorus pesticides (OPs) pesticides, which was obtained by cloning VL and VH genes from hybridoma cells secreting monoclonal antibody, was used to develop a one-step enzyme-linked immunosorbent assaydetection (ELISA) for the detection of parathion, phoxim, quinalphos, and dichlofenthion [51]
Summary
Pesticides and veterinary drugs are indispensable for increasing food production, as well as improving animal breeding and aquaculture [1]. These methods provide abundant qualitative and quantitative information of the residues with high accuracy. These systems are limited by complicated sample pre-treatments and require highly trained technicians and expensive equipment [8]. Molecules 2020, 25, 3590 techniques [11] provide relatively convenient and highly sensitive strategies for the determination of pesticides and veterinary drugs.sensitive. The accuracy precision ofofrapid methods are not as relatively convenient and highly strategies for theand determination pesticides and veterinary good those of techniques, thesemethods methods used complementarily to drugs. Techniques, these methods can be used complementarily to instrumental methods, as novel analysis the rapid and sensitive detection of pesticides and veterinary pre-screening methods formethods detectionfor in large-scale samples.
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