Abstract
Rapid detection of carbapenem resistant Klebsiella pneumoniae directly from positive blood cultures during an outbreak in the Tuscany region in Italy
Highlights
In an era of increasing drug resistance, rapid detection and determination of the molecular mechanisms involved in antimicrobial resistance is pivotal for successful treatment of bloodstream infections
At the Bacteriology Unit of the Pisa University Hospital (Pisa, Italy), Escherichia coli and Klebsiella pneumoniae are the prevalent species isolated from blood cultures (BCs) [10]
Tuscany, E. coli is still sensitive to most antibiotics, carbapenem resistant strains of K. pneumoniae have developed and spread in the community and in healthcare settings, first as K. pneumoniae strains harbouring the KPC carbapenemase gene (KPC-Kp), and more recently harbouring the NDM gene (NDM-Kp) [11,12]
Summary
In an era of increasing drug resistance, rapid detection and determination of the molecular mechanisms involved in antimicrobial resistance is pivotal for successful treatment of bloodstream infections. At the Bacteriology Unit of the Pisa University Hospital (Pisa, Italy), Escherichia coli and Klebsiella pneumoniae are the prevalent species isolated from BCs [10].
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