Abstract
Laparoscopic greater curvature plication (LGCP) is a new restrictive bariatric procedure, which has a similar restrictive mechanism like laparoscopic sleeve gastrectomy (LSG) without potential risk of leak. Aim of the study was to compare 2-year outcomes of LSG and LGCP. Multicenter prospective randomized trial was started in 2010. A total of 54 patients with morbid obesity were allocated either to LGCP group (n=25) or LSG group (n=27). Main exclusion criteria were: ASA>III, age>75 and BMI>65kg/m(2). There were 40 women and 12 men, and the mean age was 42.6±6.8years (range 35-62). Data on the operation time, complications, hospital stay, body mass index loss, percentage of excess weight loss (%EWL), loss of appetite and improvement in comorbidities were collected during the follow-up examinations. All procedures were completed laparoscopically. The mean operative time was 92.0±15min for LSG and 73±19min for LGCP (p>0.05). The mean hospital stay was 4.0±1.9days in the LSG group and 3.8±1.7days in LGCP group (p>0.05). One year after surgery, the mean %EWL was 59.5±15.4% in LSG group and 45.8±17% in LGCP group (p>0.05). After 2years, mean %EWL was 78.9±20% in the LSG group and 42.4±18% in the LGCP group (p<0.01). After 3years, mean %EWL was 72.8±22 in the LSG group and only 20.5±23.9 in the LGCP group (p<0.01). Loss of feeling of hunger after 2years was 25% in LGCP group and 76.9% in the LSG group (p<0.05). The comorbidities including diabetes, sleep apnea and hypertension were markedly improved in the both groups after surgery. The short-term outcomes demonstrated equal effectiveness of the both procedures, but 2-year follow-up showed that LGCP is worse than LSG as a restrictive procedure for weight loss.
Published Version
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