Abstract

Background and Aims:Increased gastric acid secretion, pepsin, alcohol and aspirin usage, stress, and breakdown of the mucosal barrier are the well-known etiologic factors in peptic ulcer. Long-lasting fasting is another potential factor. In this study, we aimed to assess the effects of Ramadan intermittent fasting on peptic ulcer complications. Materials and Methods:Retrospectively, data of patients operated for peptic ulcer complications between 1962 and 2012 were recorded. Complications were defined as duodenal ulcer perforation, gastric ulcer perforation, marginal ulcer perforation, and bleeding. Patients were grouped into two as: Group 1: patients operated during Ramadan, and Group 2: patients operated in times other than Ramadan. Results:Totally, 1460 patients were operated; 985 (67,5%) for duodenal ulcer perforation, 193 (13,2%) for gastric ulcer perforation, 101 (6,9%) for marginal ulcer perforation, and 181 (12,4%) for bleeding. For all patients, the mean age was 39,38±13,49 years, and the male ratio was 89,4%. The mean fasting period for the last 51 years was 13,89 hours. The mean number of operations for duodenal, gastric, and marginal ulcer perforations, bleeding, and totally all complications in one Ramadan month were 2,51, 0,67, 0,29, 0,47, and 3,94, respectively. The mean numbers for these complications in a month other than Ramadan were 1,28, 0,28, 0,15, 0,28, and 2,24, respectively. There was statistically significant difference between Group 1 and Group 2 (p

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