Radiopacity of tantalum oxide nanoparticle filled resins

Abstract

Objectives: Radiopacity of composite resins allows radiographic distinction of existing restorations and recurrent caries. Current composites must be supplemented with heavy metal-containing glasses or minerals to achieve a desired radiopacity. The purpose of this study was to evaluate the radiopacity of Tantalum oxide (Ta 2O 5) filled resins at varying percentage loadings. Methods: Methacrylate functionalized Ta 2O 5 nanoparticles (<50 nm) in methanol-dissolved or powder forms were mixed into either glycerol dimethacrylate (GDMA) or a bisGMA, TEGDMA, bisEMA mixture (GTE). Specimens were made in a split brass mold (2×2×15 mm) and compared with an aluminum stepwedge (99.5% pure Al) and a dentin slice of the same thickness. Kodak Ultraspeed periapical X-ray film on a lead plate at a target distance of 45 cm was exposed at 70 kVp and 10 mA, for 0.5 s and processed automatically. Optical density was measured ( n=3) with an RMI Processor Control Densitometer. Radiopacity was calculated as percent relative linear attenuation coefficient (Alpha). ANOVA and Student–Newman–Keuls comparisons were used to determine significance at the 95% confidence level. Results: Radiopacity increased significantly with Ta 2O 5 loading ( p=0.001). Ta 2O 5 nanoparticle filled resins enter the optimal range of diagnostic detectability ( α=150–250) at 50 wt.% and approach equivalence with enamel at approximately 70 wt.%. Significance: The introduction of tantalum oxide nanoparticle filler has potential as a miscible component of a resin composite to provide radiopacity for microfiller-type restorative materials and to circumvent the need for hydrolysis-prone glass reinforcing fillers.