Abstract
SummaryIntraperitoneally injected 35SO4ppeared rapidly in the blood and in the prostate glands of the 2-year-old mouse. Most of the prostate 35S was in the tissue proper with small amounts in the blood. The amounts of soluble 35S of prostate glands were greatest at 1 hr and least at 125 hr after 35S injection. The amounts of nonsolu-ble 35S (not removable by washing with formalin solution) decreased much more gradually than the soluble 35S. Consequently, the nonsoluble 35S amounted to 1 % of the total prostate 35S at 1 hr and to about 100% at 125 hr.The amounts of nonsoluble 35S were the same for both the ventral and lateral prostatic lobes at the various time points after the injection. The nonsoluble 35S increased to a peak at 5 hr, decreased to half the peak at 25 hr, and it continued to decrease with time.At 10 min after its injection, 35S was detectable in the epithelial cells and lumen of the acinus by radioautography. The amounts of 35S in the epithelial cells increased from relatively large at 1 h...
Published Version
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