Radical resection and analysis of surgical outcome for carcinoma of body and tail of pancreas

Abstract

Objective To explore the radical (RO) resection rate and surgical outcome for the carcinoma of body and tail of the pancreas.Methods The clinical and operative data and follow-up Results of 214 patients with the carcinoma of body and tail of the pancreas were analyzed retrospectively.Results One hundred and twenty of the 214 patients with the carcinoma of body and tail of the pancreas underwent surgical treatment,the overall resection rate was 59.2% (71/120),and the R0 resection rate was 40.8% (49/120).Compared with other treatments,the patients receiving R0 resection had smaller size,lower lymph node involvement and peri-pancrcatic organ involvement.The radical resection rates for TNM stage Ⅰ ,Ⅱ and Ⅲ patients were 100%,100% and 87.5%,respectively,which were significantly higher than those in stage IV A (29% ) and IVB(0% ) (P＜ 0.01 ).Moreover,the overall 1,3 and 5-year survival rates in the total resection of the carcinoma of body and tail of the pancreas were 14.5%(31/214),7.0%(15/214) and 2.4%(5/214),respectively,which were significantly better than those in the palliative resection group (9.1%,0 and 0),bypass operarion and laparotomy group (12.2%,0 and 0) and non-surgical group (1.20%,0 and 0)(P＜0.01).Conclusions The early diagnosis of the carcinoma of body and tail of the pancreas is crucial for increase in radical resection rate.The radical resection plays an important role in the improvement of surgical treatment. Key words: Pancreatic neoplasm; Body and tail of the pancreas; Radical resection; Resection rate; Survival rates