Radical Chain Oxidation of Cumene in the Presence of Different Supramolecular Systems Containing Oxygen Radical Anion

Abstract

Background. In most publications on the problems associated with reactive oxygen species, highlights their destructive effect on the membranes, nucleic acids and proteins. But many researchers overlooked the vast array of data showing the absolute necessity of reactive oxygen to vital processes. So many empirical data are in conflict with established in classical biochemistry scheme in which reactive oxygen species are seen only as hyperactive chemical particles that can disrupt normal harmonious progress of biochemical processes. In this regard, the study of superoxide anion role in the radical-chain oxidation processes is important, where its function as mediator remains virtually unexplored.Objective. The aim is to research the process of initiated cumene oxidation in the presence of different supra­molecular systems containing anion radical oxygen.Methods. The paper used the equilibrium solutions of supramolecular complexes KO2*crown-ether, for which ba­lance achieving time was estimated by measuring the electrical conductivity. The cumene oxidation kinetics in the presence of oxygen radical anion was monitored by gas volumetric method. To study the influence of the cation nature on the experimental mixture oxidation, we used various crown ethers to form supramolecular systems KO2*crown in DMSO.Results. It was stated that effectiveness of the complex action depends on the crown-ether nature, which allows choosing the most optimal system for the inhibiting mixture preparation.Conclusions. Our studies allow choosing the best mode and the complex structure – a source of oxygen anion radical, depending on the objectives and goals of the experiment. The received data can have significant value in studying the role of reactive oxygen species in biochemical processes.