Abstract
Objective: Platinum-based chemotherapy and bevacizumab is one of the best options for upfront treatment of stage IVB cervical cancer, resulting in extending survival rate by 5.5 months over platinum-based chemotherapy alone. Often after treatment, distant metastasis have resolved, and there is a questionable benefit for radiation of the primary tumor. We aim to investigate the effect on progression free survival (PFS) of adjuvant full pelvic radiation on chemotherapy regimens containing bevacizumab in women with stage IVB cervical cancer.
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