Abstract
We conducted a retrospective study from 2010-2018 among patients at Kaiser Permanente Northern California (KPNC). Self-reported racial ethnic groups included Caucasian, African American, Hispanic, Asian, and Other. Kaplan Meier and Cox regression analyses were used to evaluate differences in race, age, stage, and treatment utilization in relation to overall survival.
Highlights
Pancreatic cancer is the 12th most common cancer in the world, accounting for 2.7% of all cancers diagnosed [1], and it is the 3rd leading cause of death by cancer in the United States. 1-year and 5-year survival rates, combining all stages, is 27% and 6%, respectively [1]
A total of 3,799 patients were diagnosed with pancreatic ductal adenocarcinoma from 2010-2018
Studies have identified differences in distribution of tobacco use and obesity in patients of different races diagnosed with pancreatic cancer, speculating that increased pancreatic cancer risk and worse pancreatic-cancer related survival seen in African American patients could be partly attributed to differences in habits and habitus [11,12]
Summary
Pancreatic cancer is the 12th most common cancer in the world, accounting for 2.7% of all cancers diagnosed [1], and it is the 3rd leading cause of death by cancer in the United States. 1-year and 5-year survival rates, combining all stages, is 27% and 6%, respectively [1]. Does pancreatic cancer have an overall low survival rate, multiple studies have shown that African Americans diagnosed with pancreatic cancer have worse outcomes. African American patients are less likely to be recommended surgery, to undergo surgery when recommended (OR 0.66), and to receive adjuvant therapy [2,3,4]. Studies have identified differences in distribution of tobacco use and obesity in patients of different races diagnosed with pancreatic cancer, speculating that increased pancreatic cancer risk and worse pancreatic-cancer related survival seen in African American patients could be partly attributed to differences in habits and habitus [11,12]. This study evaluates survival outcomes of pancreatic ductal adenocarcinoma patients treated at a large, integrated health system and whether there are differences based on race
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