Abstract
An efficient receptor-mediated delivery system has been developed using preformed complexes of Quantum Dots (QDs) and the Epidermal Growth Factor (EGF) ligand. Liposomes are either loaded or surface modified combining two colours of QDs probes. The dual labelling strategies involve only biotin-streptavidin interactions and do not require further purification from free QDs-EGF. Specific uptake of QD-EGF-labelled liposomes is detected in live cells as colocalisation of both dots.
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