Quantitative study of dual-perfusion characteristic of liver on normal living bodies by dual-energy CT

Abstract

objective Using iodimetric analysis of dual-energy CT,to explore the dual perfusion amount and proportion of hepatic artery and portal vein in different hepatic lobes on normal living bodies. Methods A total of 77 patients without hepatic diseases underwent contrast-enhanced upper abdomen dual-energy CT scanning.The raw data were transferred to the workstation for postprocessing.ROI were selected,then the iodine content in arterial phase,portal phase and delay phase were calculated automatically.The differences of these measures (iodine content and hepatic artery to portal vein perfusion ratio of the left hepatic lobe,right hepatic lobe and caudate lobe) in the left,right and caudate lobe of liver were detected by using ANOVA test. Results The iodine concentration in the caudate lobe was (851±35) μg/L from hepatic artery and (2912±78) μg/L from portal vein.The iodine concentration in the left hepatic lobe was (445±34) μg/L from hepatic artery and (2373±77) μg/L from portal vein.The iodine concentration in the right hepatic lobe was (504±30) μg/L from hepatic artery and (2515±78) μg/L from portal vein.The perfusion condition (amount of blood supply) of caudate lobe showed a significant statistic difference from the left and right hepatic lobe (P 0.05).The proportions of blood supply from hepatic artery and portal vein (hepatic artery/portal vein) were different among the three hepatic lobes,which was (28.41±3.42) % in left lobe,(35.76±5.80) % in right lobe and (49.92±4.63) % in caudate lobe,respectively (F=5.36,P<0.01). Conclusion Dual-energy CT can be used to study the dual-perfusion condition of the liver.On normal living bodies,the hepatic artery and portal vein perfusion in caudate lobe are different from those in left and right lobes. Key words: Hepatic; Tomography,X-ray computed; Spectral imaging