Abstract
Computed tomography and magnetic resonance imaging have been used for anatomical imaging of various organs and tissues. In addition to high resolution image, high-speed imaging will enable these modalities to provide not only anatomic but also functional imaging. Therefore, nuclear medicine should take the direction such as quantitative nuclear imaging based on the organ function and blood flow. In this paper, several examples of quantitative nuclear imaging for therapeutic interventions were reviewed in the field of neurology, cardiology, and oncology. As a result, functional imaging by single photon emission computed tomography (SPECT) should approach positron emission tomography (PET) in excellence. In conclusion, advances in tracer and related technology highlight the need for a sensitive imaging technique to quantify changes in cellular function based on the tracer principle. Appropriate uses of quantitative nuclear imaging will ensure its role in clinical care in the next century.
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