Abstract

Quantitative evaluation of radioisotope (RI) cisternography was performed by single photon emission computed tomography (SPECT) in eight patients suspected of chronic hydrocephalus or malfunction of a shunt system, showing symptoms for 2 to 24 months and one control patient with cerebrospinal fluid (CSF) leakage ten years after head trauma. Regular evaluations were scheduled after the injection of 1 ml of 1 mCi Indium-111 diethylene triamine pentaacetic acid. The region of interest, about 1.3 cm in radius and 0.8 cm in height, was placed in the cisterna magna (CM), lateral cistern Sylvii (LCS), basal cistern (BC), interhemispheric cistern (IHC), and in the lateral ventricle (LV) using a reconstructed image of a horizontal section by SPECT. Decay curves were calculated with estimating decreasing count of RI each time by the least square method.

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