Abstract
1Quantification of EEG signals, using frequency analysis and/or amplitude analysis, permits the detection and characterization of certain psychoactive drug effects, both in patients and in normal volunteers.2In non-patients the occurrence of the main EEG rhythms is differentially changed by minor tranquilizers, neuroleptics, antidepressants, stimulants and hallucinogens. Such data have predictive value for therapy.3Amplitude analysis, especially when performed interhemispherically, also permits the detection of such drug effects. These are manifested by significant changes in either the mean amplitudes, their time-course variability, or both. The data are especially informative when the pre-postdrug relationships are taken into consideration.
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