Abstract
Study of sorption of perphenazine onto bead O-(3-phenoxy-2-hydroxypropyl)cellulose revealed that in equilibrium the partition law is the ruling one. Partition coefficient proved to be independent of bulk concentration of sorbate. Similar results were obtained with bovine serum albumin applied as sorbate. As an easily available measure of hydrophobicity of polymer matrices, coefficient p proved to be particularly useful in screening the properties of carriers applied as stationary phase for hydrophobic interaction chromatography.
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Schedule a callMore From: Journal of Chromatography B: Biomedical Sciences and Applications
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