Abstract
The possibility of applying near-infrared (NIR) spectroscopy to monitor 13 active components (phenolic acids, flavonoids, and sesquiterpene lactones) in Arnicae flos was studied. The preprocessing of the spectra were performed by using the conventional Golay-Savitzky procedure and the newly developed step-by-step filter. The results obtained show that the step-by-step filter derivatives provide a better signal-to-noise ratio at a lower convolution window. Better calibration for the content of protocatechuic acid, chlorogenic acid, caffeic acid, p-cumaric acid, ferulic acid, isoquercitrin, and quercetin were obtained by step-by-step filter derivatives, compared to the direct raw spectra processing and the Golay-Savitzky approach. Although the step-by-step filter substantially reduces the spectral distortion, the convolution procedure leads to loss of spectral points in the red end of the spectral curve. Probably for this reason this approach shows better calibration only in seven of the monitored 13 active components.
Highlights
The use of herbal medicinal products (HMP) is becoming increasingly relevant for modern healthcare as an alternative to conventional medicine [1]
Shows some obvious advantages – better signal-to-noise ratio and lower spectra distortion at a low convolution window, it loses a substantial number of spectral points in the red end of the spectral curve
This is probably the reason this approach shows better calibration only in 7 of the 13 active components monitored
Summary
The use of herbal medicinal products (HMP) is becoming increasingly relevant for modern healthcare as an alternative to conventional medicine [1]. In order to achieve reproducible quality and safety of the HMP, the raw materials from which they are harvested should be subjected to a comprehensive qualitative and quantitative analysis to ensure their authenticity and compliance with the pharmacopoeial requirements [3]. The subject of this paper is the plant substance Arnicae flos obtained from the species Arnica montana L. In 1998, Lange et al [9] evaluated the use of Arnicae flos in Europe at over 50,000 kg of dry substance, and according to Franke et al [10], over 20,000 kg of dried flowers are required to cover the annual needs of the German market alone. The raw material is harvested both from wild populations and from cultivation
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
