Abstract
Background Interstitial myocardial fibrosis is a histological hallmark of non-ischemic dilated cardiomyopathy (DCM), and may play an important role in adverse remodelling and progressive systolic dysfunction. T1-mapping enables noninvasive assessment of diffuse fibrosis by quantification of myocardial extracellular volume fraction (ECV). We hypothesized that CMR would identify a raised ECV in DCM which would correlate with the degree of systolic dysfunction.
Highlights
Interstitial myocardial fibrosis is a histological hallmark of non-ischemic dilated cardiomyopathy (DCM), and may play an important role in adverse remodelling and progressive systolic dysfunction
Univariate linear regression analysis revealed that indexed left ventricular end diastolic volume, heart rate, gender and left ventricular ejection fraction (LVEF) were significantly associated with extracellular volume fraction (ECV)
ECV is expanded in DCM in proportion to the degree of LV systolic dysfunction
Summary
Aamir Ali1*, Ankur Gulati, Tevfik F Ismail, Kaushiga Krishnathansan, Nizar Ismail, Evangelia Nyktari, Navtej Chahal, Claire E Raphael, Rick Wage, Taigang He1, Peter D Gatehouse, David Firmin, Peter Kellman, Dudley Pennell, Andrew E Arai, Sanjay K Prasad. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. From 16th Annual SCMR Scientific Sessions San Francisco, CA, USA. 31 January - 3 February 2013
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
