Abstract
We derive analytic expressions in the form of an implicit function for the system size, volume shape, refractive-index-mismatched boundary, and source-detector separation, to determine the concentrations of absorbing substances in highly scattering media such as human tissue. The basis of our derivation is the microscopic Beer-Lambert law that holds true when we trace a zigzag photon path within the medium. The validity of our prediction is evaluated by Monte Carlo simulations for transmission and reflection from an infinitely wide, 20-mm-thick slab. Quantitative spectroscopies are compared by measuring a tissue-like, liquid phantom using photon density waves modulated at 100 MHz, where the absorption of the medium is changed (the absorption coefficient μa ≈ 0.002–0.02mm−1 at 786 nm).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
