Abstract
Objective To evaluated the quality of life of maintenance hemodialysis (MHD) and CAPD patients and to discuss the influence factors of quality of life of MHD and CAPD patients. Methods The objects' clinical and questionnaire data were obtained from the Department of Nephrology and Blood Purification Center, the First Affiliated Hospital of Zhengzhou University, from July to September 2016, which inclued 118 MHD patients and 76 CAPD patients.The quality of life of MHD and CAPD patients was evaluated through the application of KDQOL-SFTM 1.3 version. At the meantime, related indexes reflecting nutrition and the adequecy of hemodialysis of MHD and CAPD patients were screened. Results The KDTA score of MHD patients was (62.4±11.3), SF-36 score was (58.3±17.9), significantly lower than the general population(P<0.05). In KDTA and SF-36, the score of 11 fractal dimensions was slightly higher than the United States, and the scores of 6 fractal dimensions was slightly higher than Spain.Compared with the survey data in Guangzhou, scores of all fractal dimensions were obviously improved and the same as survey data of Shenyang and Hefei.The KDTA score of CAPD patients was (71.4±8.9), SF-36 score was (61.6±16.3), significantly lower than the general population(P<0.05). In KDTA and SF-36, the score of 7 fractal dimensions was significantly higher than Hongkong, and the rest of which were all relatively low than Hongkong.Compared with the survey data in Guangzhou, scores of all fractal dimensions were obviously improved and the same as survey data of Shenyang and Hefei.The KDTA and SF-36 overall scores of MHD patients were significantly lower than the CAPD patients(P<0.05). In 11 fractal dimensions, the scores of all fractal dimensions of CAPD patients were higher than MHD patients and showed significant differences in EKD, BKD, WS, CF, QSI, SexF, SoS and PS(P<0.05). In 8 fractal dimensions’ scores of SF-36, besides PF, SF and Energy, the other fractal dimensions’ scores of CAPD patients were all higher than MHD patients and showed significant differences in PF, RP, BP, EWB, RE and SF(P<0.05). The general data for the MHD patients showed that the quality of life existed differences (P<0.05) among the sex, literacy, annual household income, the conditions of health insurance, the primary diseases and the dialysis age, and also had a correlation (P<0.05) with the scores of SAG, ALB, HB, Kt/V, iPTH, Ca×P. Multiple-factor analysis showed that dialysis age, sex (female), the primary disease (DN), iPTH, Kt/V, the score of SGA was the independent risk factors for the quality of life of the MHD patients, of which dialysis age was a long-time effect factor. The general data for the CAPD patients showed that professional conditions, the conditions of health insurance, the causes of primary diseased and the dialysis age existed differences (P<0.05), and also had a correlation (P<0.05) with the score of SAG, ALB, HB, Kt/V, multiple-factor analysis showed that the primary disease(DN), Kt/V, ALB, the score of SGA were the independent risk factors for the quality of life of the CAPD patients. Conclusions MHD and CAPD patients have a low quality of life, there are differences between developing and developed country.Diabetic Nephropathy, Kt/V, SGA are the common independent risk factors for the quality of life of the MHD and CAPD patients. Key words: Maintenance hemodialysis; CAPD; Quality of life
Published Version
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