Abstract

Background:Peritoneal dialysis (PD) is gaining track as an efficient/affordable therapy in poor settings. Yet, there is little data regarding differences in quality of life (QoL) of primary caregivers (PCG) of patients in PD and hemodialysis (HD).Aim:To compare the QoL of PCG of patients in PD and HD from an upper middle-income population in a Mexican city.Methods:Cross-sectional study was carried out with PCG of patients in PD (n=42) and HD (n=95) from 4 hospitals (response rate=70.2%). The SF 36-item QoL questionnaire, the Zarit burden interview, and the Goldberg anxiety/depression scale were used. Mean normalized scores for each QoL domain were compared by dialysis type. Adjusted odds were computed using logistic regression to determine the probability of low QoL (<70% of maximum possible score resulting from the added scores of the 8 dimensions).Results:The PD group had higher mean scores for emotional role functioning (+10.6; p=0.04), physical functioning (+9.2; p=0.002), bodily pain (+9.2; p=0.07), social functioning (+5.7; p=0.25), and mental health (+1.3; p=0.71); the HD group had higher scores for physical role functioning (+7.9, p=0.14), general health perception (+6.1; p=0.05), and vitality (+3.3; p=0.36). A non-significant OR was seen in multivariate regression (1.51; 95% CI 0.43-5.31). Zarit scores were similar, but workload levels were lower in the PD group (medium/high: PD 7.2%, HD 14.8%). Anxiety (HD 50.5%, PD 19%; p<0.01) and depression (HD 49.5%, PD 16.7%; p<0.01) were also lower in the PD group.Conclusion:Adjusted analysis showed no differences in the probability of low QoL between the groups. These findings add to the value of PD, and strengthen its importance in resource-limited settings.

Highlights

  • An estimated 5-10 million people die every year from chronic kidney disease[1]

  • While HD is by far the most common modality worldwide, especially in developed countries[6], peritoneal dialysis (PD) is becoming a major alternative in low- and middleincome settings[5,7,8,9,10], as it has shown to be the most economically efficient dialysis modality[11,12], two out of three patients who receive PD live in developing nations[13]

  • The vast majority of the participant primary caregivers (PCG) accompanied their patient to the medical appointments and reported duties associated with the illness and dialysis process

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Summary

Introduction

An estimated 5-10 million people die every year from chronic kidney disease[1] This is an irreversible illness that progressively erodes the patients’ health and quality of life (QoL). There is little data regarding differences in quality of life (QoL) of primary caregivers (PCG) of patients in PD and hemodialysis (HD). Adjusted odds were computed using logistic regression to determine the probability of low QoL (

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