Abstract
The aim of the study was to examine the quality of life and clinical features of non-psychotic mental disorders in patients with acute and chronic pancreatitis. Polymorphic mental disorders of different clinical content and severity in most cases not only comorbid diseases of the pancreas, but often are the first earliest clinical manifestations of the disease. The data on clinical and psychopathological features of non-psychotic mental disorders in patients with acute and chronic pancreatitis are given. The share of cardinal syndromes such as asthenic-neurotic and anxious-depressive was established and described. The study was conducted using the following methods: clinical psychiatric questionnaire of common type MOS Short Form-36 Health Survey (SF-36) and methods of mathematical processing. The sample included 131 patients with acute and chronic pancreatitis. Clinical variant of acute and chronic pancreatitis debut were the features of mental disorders and psychotic-pathologic structure of non-psychotic mental disorders. Various indicators of quality of life in acute and chronic pancreatitis in presence of psychotic disorders were revealed.
Highlights
Ȼ ɬɟɱɟɧɢɟ ɩɨɫɥɟɞɧɢɯ 30 ɥɟɬ ɨɬɦɟɱɚɟɬɫɹ ɞɜɭɤɪɚɬɧɵɣ ɪɨɫɬ ɱɢɫɥɚ ɛɨɥɶɧɵɯ ɨɫɬɪɵɦ ɢ ɯɪɨɧɢɱɟɫɤɢɦ ɩɚɧɤɪɟɚɬɢɬɨɦ. ɂɧɜɚɥɢɞɢɡɚɰɢɹ ɞɚɧɧɵɯ ɛɨɥɶɧɵɯ ɞɨɫɬɢɝɚɟɬ 15% [3]
Ʉɥɢɧɢɤɨɩɫɢɯɨɩɚɬɨɥɨɝɢɱɟɫɤɚɹ ɱɚɫɬɶ ɢɧɬɟɪɜɶɸ ɫɨɞɟɪɠɚɥɚ ɫɬɚɧɞɚɪɬɧɵɟ ɦɟɠɞɭɧɚɪɨɞɧɵɟ ɤɪɢɬɟɪɢɢ ɩɫɢɯɢɱɟɫɤɢɯ ɪɚɫɫɬɪɨɣɫɬɜ ɩɨ ɆɄȻ-10 ɢ ɨɪɢɝɢɧɚɥɶɧɵɟ ɤɪɢɬɟɪɢɢ ɨɰɟɧɤɢ ɩɫɢɯɢɱɟɫɤɢɯ ɧɚɪɭɲɟɧɢɣ, ɪɚɡɪɚɛɨɬɚɧɧɵɟ ɫɨɛɫɬɜɟɧɧɨɥɢɱɧɨ ɧɚ ɷɬɚɩɟ ɩɨɞɝɨɬɨɜɤɢ ɢɫɫɥɟɞɨɜɚɧɢɹ ɢ ɩɨɡɜɨɥɹɸɳɢɟ ɭɬɨɱɧɹɬɶ ɛɢɨɝɪɚɮɢɱɟɫɤɢɟ ɞɚɧɧɵɟ, ɭɪɨɜɟɧɶ ɨɛɪɚɡɨɜɚɧɢɹ, ɤɭɥɶɬɭɪɚɥɶɧɵɟ ɨɫɨɛɟɧɧɨɫɬɢ ɦɢɤɪɨɫɪɟɞɵ, ɫɨɰɢɚɥɶɧɵɣ ɢ ɫɟɦɟɣɧɵɣ ɫɬɚɬɭɫ, ɧɚɥɢɱɢɟ ɜ ɬɟɱɟɧɢɢ ɠɢɡɧɢ ɫɬɪɟɫɫɨɜɵɯ ɫɢɬɭɚɰɢɣ. ɂɫɩɨɥɶɡɨɜɚɥɫɹ ɫɬɚɧɞɚɪɬɢɡɢɪɨɜɚɧɧɵɣ ɨɩɪɨɫɧɢɤ «SF-36 Health Status Survey», ɤɨɬɨɪɵɣ ɹɜɥɹɟɬɫɹ ɧɚɢɛɨɥɟɟ ɪɚɫɩɪɨɫɬɪɚɧɟɧɧɵɦ ɨɛɳɢɦ ɨɩɪɨɫɧɢɤɨɦ ɞɥɹ ɢɡɭɱɟɧɢɹ ɤɚɱɟɫɬɜɚ ɠɢɡɧɢ ɜ ɩɨɩɭɥɹɰɢɢ ɢ ɩɪɢ ɪɚɡɥɢɱɧɵɯ ɫɨɦɚɬɢɱɟɫɤɢɯ ɡɚɛɨɥɟɜɚɧɢɹɯ, ɩɨɡɜɨɥɹɸɳɢɦ ɨɰɟɧɢɜɚɬɶ ɭɞɨɜɥɟɬɜɨɪɟɧɧɨɫɬɶ ɛɨɥɶɧɵɯ ɭɪɨɜɧɟɦ ɫɜɨɟɝɨ ɮɭɧɤɰɢɨɧɢɪɨɜɚɧɢɹ ɜ ɭɫɥɨɜɢɹɯ ɛɨɥɟɡɧɢ [9]. ɋɬɚɬɢɫɬɢɱɟɫɤɚɹ ɨɛɪɚɛɨɬɤɚ ɪɟɡɭɥɶɬɚɬɨɜ ɢɫɫɥɟɞɨɜɚɧɢɹ ɩɪɨɜɨɞɢɥɚɫɶ ɫ ɩɨɦɨɳɶɸ ɩɚɤɟɬɚ ɩɪɨɝɪɚɦɦ Statistica v.6.1®[2]. ɋɪɟɞɧɢɟ ɩɨɤɚɡɚɬɟɥɢ ɩɪɟɞɫɬɚɜɥɟɧɵ ɤɚɤ ɫɪɟɞɧɹɹ ɚɪɢɮɦɟɬɢɱɟɫɤɚɹ ɢ ɫɬɚɧɞɚɪɬɧɚɹ ɨɲɢɛɤɚ (M ± m)
4. ɇɚɪɹɞɭ ɫ ɤɥɢɧɢɤɨ-ɩɫɢɯɨɩɚɬɨɥɨɝɢɱɟɫɤɢɦɢ ɩɪɢɡɧɚɤɚɦɢ ɧɟɩɫɢɯɨɬɢɱɟɫɤɢɯ ɩɫɢɯɢɱɟɫɤɢɯ ɪɚɫɫɬɪɨɣɫɬɜ, ɢɫɫɥɟɞɨɜɚɧɢɟ ɤɚɱɟɫɬɜɚ ɠɢɡɧɢ ɭ ɞɚɧɧɵɯ ɩɚɰɢɟɧɬɨɜ ɦɨɠɟɬ ɫɥɭɠɢɬɶ ɞɢɚɝɧɨɫɬɢɱɟɫɤɢɦ ɦɚɪɤɟɪɨɦ ɢ ɛɵɬɶ ɢɫɩɨɥɶɡɨɜɚɧɨ ɩɪɢ ɩɫɢɯɨɤɨɪɪɟɤɰɢɨɧɧɵɯ ɦɟɪɨɩɪɢɹɬɢɹɯ
Summary
Ȼ ɬɟɱɟɧɢɟ ɩɨɫɥɟɞɧɢɯ 30 ɥɟɬ ɨɬɦɟɱɚɟɬɫɹ ɞɜɭɤɪɚɬɧɵɣ ɪɨɫɬ ɱɢɫɥɚ ɛɨɥɶɧɵɯ ɨɫɬɪɵɦ ɢ ɯɪɨɧɢɱɟɫɤɢɦ ɩɚɧɤɪɟɚɬɢɬɨɦ. ɂɧɜɚɥɢɞɢɡɚɰɢɹ ɞɚɧɧɵɯ ɛɨɥɶɧɵɯ ɞɨɫɬɢɝɚɟɬ 15% [3]. Ȼ ɬɟɱɟɧɢɟ ɩɨɫɥɟɞɧɢɯ 30 ɥɟɬ ɨɬɦɟɱɚɟɬɫɹ ɞɜɭɤɪɚɬɧɵɣ ɪɨɫɬ ɱɢɫɥɚ ɛɨɥɶɧɵɯ ɨɫɬɪɵɦ ɢ ɯɪɨɧɢɱɟɫɤɢɦ ɩɚɧɤɪɟɚɬɢɬɨɦ. Ɉɬɦɟɱɟɧɧɚɹ ɜɨ ɦɧɨɝɢɯ ɢɫɫɥɟɞɨɜɚɧɢɹɯ ɜɵɫɨɤɚɹ ɱɚɫɬɨɬɚ ɬɪɟɜɨɠɧɵɯ ɢ ɞɟɩɪɟɫɫɢɜɧɵɯ ɪɚɫɫɬɪɨɣɫɬɜ ɩɪɢ ɫɨɦɚɬɢɱɟɫɤɢɯ ɡɚɛɨɥɟɜɚɧɢɹɯ ɨɩɪɟɞɟɥɹɟɬ ɱɪɟɡɜɵɱɚɣɧɭɸ ɚɤɬɭɚɥɶɧɨɫɬɶ ɤɨɪɪɟɤɰɢɢ ɞɚɧɧɵɯ ɫɢɦɩɬɨɦɨɜ ɭ ɩɚɰɢɟɧɬɨɜ ɫ ɩɚɧɤɪɟɚɬɢɬɨɦ. Ȼɫɟ ɛɨɥɟɟ ɚɤɬɭɚɥɶɧɨɣ ɹɜɥɹɟɬɫɹ ɩɪɨɛɥɟɦɚ ɧɟ ɩɪɨɫɬɨ «ɜɵɠɢɜɚɧɢɹ» ɛɨɥɶɧɨɝɨ, ɧɨ ɢ ɤɚɱɟɫɬɜɚ ɟɝɨ ɠɢɡɧɢ ɤɚɤ ɨɰɟɧɤɢ ɭɫɩɟɲɧɨɫɬɢ ɥɟɱɟɧɢɹ ɢ ɪɟɚɛɢɥɢɬɚɰɢɢ
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