Abstract
To compare the evolution of quality of life (QoL) in nursing home residents (NHRs) with and without (hospitalization for) pneumonia. Twelve-month prospective, observational study. Participants of the Incidence of pNeumonia and related ConseqUences in nursing home Resident (INCUR) study were included. The INCUR study included 800 NHRs in France for which comprehensive assessments were performed at baseline, 6months, and 12months in 2012-2013. Participants' health related QoL was assessed at 3 time points: baseline, 6months, and 12months. NHRs with or without pneumonia and hospitalizations for this condition at any time during follow-up were compared using adjusted mixed effects linear regressions on the QoL outcome. Pre- and postpneumonia QoL were compared using a Wilcoxon signed-rank test. A total of 622 NHRs (mean age 86.2years; 73.3% women) were included; 13.8% (n= 86) died, 19.9% (n= 124) developed at least 1 episode of pneumonia and 6.4% (n= 40) were hospitalized for pneumonia. Median QoL was 70 at baseline [n= 436, interquartile range (IQR)= 50-90], 80 at 6months (n= 546, IQR= 50-90), and 76 at 12months (n= 468, IQR= 50-80). QoL in NHRs with pneumonia showed a 2-point decrease during the 12-month follow-up, whereas QoL in NHRs without pneumonia showed an 8-point increase during follow-up. QoL in NHR hospitalized for pneumonia showed a 16-point decrease during the 12-month follow-up, whereas QoL in NHRs in the control group showed a 6-point increase. In linear regressions, neither pneumonia nor hospitalization for pneumonia were significantly associated with the evolution of QoL during follow-up. No significant difference was found between pre- and postpneumonia QoL. QoL in NHRs remains stable over 12months regardless of pneumonia events but seems to decline in NHRs hospitalized for pneumonia. Uncaptured short-term variations of QoL after pneumonia and/or related hospitalizations may occur.
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