Abstract
Quality and Safety of Blood Products.
Highlights
Current Good Manufacturing Practices ensure that blood operators maintain the Safety, Quality, Identity, Potency, and Purity of blood components, criteria collectively encompassed by the acronym SQuIPP
Quality testing should ensure similarity in the SQuIPP criteria of blood components prepared by different manufacturing methods
Cell-free DNA is released by neutrophils prior to leukocyte reduction, which occurs at different times during unit preparation by the two methods used in Canada, the RBC filtration method or the whole blood filtration method
Summary
Quality testing should ensure similarity in the SQuIPP criteria of blood components prepared by different manufacturing methods. Blood components used for transfusion therapy in developed countries include platelet concentrates (PCs), red cell concentrates (RBCs), and plasma.
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