Abstract
The lawfulness of the application of the method of dermatoglyphics in the study of atopic diseases is ensured by the polygenic inheritance of signs of dermatoglyphics, on the one hand, and the pathogenetic heterogeneity of these diseases, on the other hand, as well as high informative ability of signs of dermatoglyphics as markers of diseases of hereditary and multifactorial nature. The purpose of the study is to detect differences in qualitative signs of digital dermatoglyphics between patients with atopic dermatitis, allergic rhinitis and bronchial asthma. Primary indicators of digital dermatoglyphics of sick young men and young women of the Podillia region are taken from the data bank of the research center of the National Pirogov Memorial Medical University, Vinnytsya and were used in previous studies when compared with the practically healthy population of this region. Imprints were obtained by the method of “printing ink” by Gladkova T. D. By the method of Cummins H. and Midlo Ch. a dermatological study was performed for 320 young men and young women with allergic rhinitis (n=69), bronchial asthma (n=108) and atopic dermatitis (n=143). The frequency and location of 8 types of finger patterns were subject to analysis. Statistical processing of the obtained results was carried out in the package “Statistica 6.1” using nonparametric methods. The reliability of the difference in values between independent qualitative values was determined by the formula of Weber E. (1961). The specificity of the digital typology of atopic diseases is established, which is based on the differences in the frequency and location of the whorl, central pocket and arches between the young men, except those indicated - a random pattern between young women, patients with atopic dermatitis, bronchial asthma, allergic rhinitis. Additionally, when comparing young men, patients with allergic rhinitis with patients with bronchial asthma and atopic dermatitis - ulnar loop; for bronchial asthma with patients with allergic rhinitis and atopic dermatitis - lateral pocket loop (in young men) and ulnar, lateral pocket and double loops (in young women); when comparing young men, patients with atopic dermatitis with patients with bronchial asthma, and allergic rhinitis - a random pattern.
Highlights
Atopic march is a combination of processes that consists in the predominance of certain manifestations of allergic character in different periods of human development
The classically atopic march begins in childhood in the form of atopic dermatitis, which subsequently changes with allergic rhinitis
Materials and methods Primary indices of digital dermatoglyphics of patients with atopic rhinitis, bronchial asthma and atopic dermatitis of young men and young women of the Podillia region are taken from the data bank of the research center of the National Pirogov Memorial Medical University, Vinnytsya and were used in previous studies when compared with practically healthy young men and young women [2, 7, 9]
Summary
Atopic march is a combination of processes that consists in the predominance of certain manifestations of allergic character in different periods of human development. The classically atopic march begins in childhood in the form of atopic dermatitis, which subsequently changes with allergic rhinitis. At the end of the atopic march there is bronchial asthma [3]. By manifestations of the atopic march are afflicted millions of people around the world and annual increases in incidence of atopic dermatitis and allergic rhinitis and bronchial asthma are recorded [1, 22, 31]. According to Taiwanese scientists, the incidence of atopic dermatitis, allergic rhinitis and bronchial asthma for 8 years (from 2000 to 2007) is 6.7%, 26.3% and 11.9%, respectively. Korean researchers found that the prevalence of allergic rhinitis was 24.34% for elementary school students, 13.75% for high school students and 12.17% for secondary school students [16]
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