Qualitative investigation and screening of antimicrobial activity of stem extract in Clerodendrum infortunatum plant

Abstract

Clerodendrum infortunatum is known as hill glory bower and a plant which is widely distributed throughout the whole world. Up to now, many species of C. infortunatum have been described in various indigenous systems of medicine that are used in preparation of folklore medicines for the treatment of various life-threatening diseases, and much of this plant have been very well studied for their chemical constituents and biological activities. It also is used in Unani, Ayurveda, and siddha system of medicine for many years. From Clerodendrum infortunatum many compounds, including mono-turpentine and its derivatives, sesquiterpene, diterpenoids, tri-terpentine, flavonoid, quercetin, acacetin, gallic acid, sterol and flavonoid glycoside, phenylethanoid glycoside, steroids and steroid glycosides, cyclohexylethanoids, anthraqunine, cyanogenic glycolsides, and others have been isolated and identified. In the present study, Chloroform, pet. ether, and water stem extract of Clerodendrum infortunatum obtained by Soxhlet extraction was screened to detect the presence or absence of several bioactive compounds which are reported to cure different diseases. Anti-microbial analysis of stem extract was carried out against lactobacillus, E.coli and staphylococcus aureus organisms by agar well diffusion method. It was observed that the zone was recorded against this organism. The results indicate that the chloroform, pet.ether and water extracts of C. infortunatum are having anti- microbial efficiency in controlling the microorganisms. So, Clerodendrum infortunatum is the plant which are beneficial on human health.