Abstract
Lamiaceae species are promising potential sources of natural antioxidants, owing to their high polyphenol content. In addition, increasing scientific and epidemiological evidence have associated consumption of foods rich in polyphenols with health benefits such as decreased risk of cardiovascular diseases mediated through anti-inflammatory effects. The complex and diverse nature of polyphenols and the huge variation in their levels in commonly consumed herbs make their analysis challenging. Innovative robust analytical tools are constantly developing to meet these challenges. In this review, we present advances in the state of the art for the identification and quantification of polyphenols in Lamiaceae species. Novel chromatographic techniques that have been employed in the past decades are discussed, ranging from ultra-high-pressure liquid chromatography to hyphenated spectroscopic methods, whereas performance characteristics such as selectivity and specificity are also summarized.
Highlights
Concerns over possible adverse health effects of commonly used synthetic antioxidants such as butylated hydroxytoluene (BHT) or butylated hydroxyanisole (BHA) have driven research interests towards finding antioxidants from natural sources, mainly from commonly consumed foods [1,2].Terrestrial plants constitute one of the most valuable sources of natural antioxidants in addition to other health-promoting phytochemicals [3]
The need for sensitive and accurate methods for the analysis of polyphenols is essential, as knowledge of dosage are prerequisites in evaluating health claims of food components. Classical techniques such as high-performance liquid chromatography (HPLC), thin layer chromatography (TLC), gas chromatography (GC), and capillary electrophoresis (CE), which rely on UV spectrophotometry as the detection tool, have been used for the analysis of polyphenol profiles in herbs [18]
ultra-high-performance liquid chromatography (UHPLC)-electrospray ionization (ESI)-MSn with a total run time of 35 min, for the phenolic compositional analysis of a branded extract of Rosmarinus officinalis (Table 2), where 57 compounds were identified and quantified, and of which 14 polyphenols were detected for the first time (Table S1) in this species [53]
Summary
Concerns over possible adverse health effects of commonly used synthetic antioxidants such as butylated hydroxytoluene (BHT) or butylated hydroxyanisole (BHA) have driven research interests towards finding antioxidants from natural sources, mainly from commonly consumed foods [1,2]. The need for sensitive and accurate methods for the analysis of polyphenols is essential, as knowledge of dosage are prerequisites in evaluating health claims of food components Classical techniques such as high-performance liquid chromatography (HPLC), thin layer chromatography (TLC), gas chromatography (GC), and capillary electrophoresis (CE), which rely on UV spectrophotometry as the detection tool, have been used for the analysis of polyphenol profiles in herbs [18]. These methods generally lack specificity and sensitivity and rely on the chemical nature of the analytes (chromophore). This review describes the recent (2013–2018) developments and applications of analytical methods in qualitative and quantitative studies of polyphenols following extraction, with special focus on the Lamiaceae spices
Sign-in/Register to view highlights & summary Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
