Abstract
Phytochemicals have great potency as therapeutic agents. There is continuous and urgent need to discover newtherapeutic compounds with diverse chemical structures and novel mechanism of action because there has been analarming increase in the incidence of new and re-emerging infectious diseases. Hence, the present investigation wascarried out to assess the phytoconstituents of various root extracts of Acanthospermum hispidum. The extracts weresubjected to qualitative and quantitative phytochemical analyses as per standard procedures. The results showed thatsteroids were detected in maximum number of solvent extracts (five among six solvent extracts analysed) followed byalkaloids (in four solvent extracts). Flavonoids, glycosides, phenols, saponins and tannins were absent in all the sixsolvents used for qualitative phytochemical analyses. Maximum number (five) of compounds were identified in methanoland least (one) in hexane root extract of Acanthospermum. Findings of quantitative analyses highlighted that maximumcontent of alkaloids (4.54 mg/g) were determined in aqueous extract, flavonoids (0.93 mg/g) in methanol, phenols(1.50 mg GAE/g) in aqueous, tannins (0.84 mg TAE/g) in methanol and terpenoids (3.66 %) in methanol extracts. Theresult of this study is encouraging further clinical studies to determine the potential effectiveness of particularphytochemical in vivo.
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