Qualitative analysis of the invasion free boundary problem in biofilms

Abstract

The work presents the qualitative analysis of the free boundary value problem related to the invasion model for multispecies biofilms. This model is based on the continuum approach for biofilm modeling and consists of a system of nonlinear hyperbolic partial differential equations for microbial species growth and spreading, a system of semilinear elliptic partial differential equations describing the substrate trends and a system of semilinear elliptic partial differential equations accounting for the diffusion and reaction of motile species within the biofilm. The free boundary evolution is regulated by a nonlinear ordinary differential equation. Overall, this leads to a free boundary value problem essentially hyperbolic. By using the method of characteristics, the partial differential equations constituting the invasion model are converted to Volterra integral equations. Then, the fixed point theorem is used for the uniqueness and existence result. The work is completed with numerical simulations describing the invasion of nitrite oxidizing bacteria in a biofilm initially constituted by ammonium oxidizing bacteria.