Abstract
Q&A: What can microfluidics do for stem-cell research?
Highlights
What can microfluidics do for stem-cell research? Stem-cell biology and microfluidics have both been hotbeds of research activity for the past few years, yet neither field has been able to successfully commercialize a clinical ‘killer application.’ Stem-cell behavior is exquisitely sensitive to environmental cues, and the important cues are difficult to establish, manipulate and quantify in traditional cell culture
What exactly is microfluidics? Microfluidics is the characterization and manipulation of fluids on the nanoliter or picoliter scale. e behavior and properties of fluids change as amounts decrease from the macroscale to the microscale. is means that microfluidic devices cannot be built by scaling down macroscale devices
What background do you need for microfluidics? Physics, mechanical engineering, or bioengineering backgrounds, the common feature of these being a strong mathematical foundation
Summary
What can microfluidics do for stem-cell research? Stem-cell biology and microfluidics have both been hotbeds of research activity for the past few years, yet neither field has been able to successfully commercialize a clinical ‘killer application.’ Stem-cell behavior is exquisitely sensitive to environmental cues, and the important cues are difficult to establish, manipulate and quantify in traditional cell culture. Is technique has been used to print precise patterns of proteins or protein gradients onto a surface on which cells can subsequently be cultured to investigate or control their behavior.
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