Abstract

An essential process for fatty acid digestion, absorption and assimilation is the constant replacement of mature intestinal epithelial cells by differentiating stem cells. Free fatty acids (FFA) and PYY may act in concert to alter mucosal cell differentiation through the cytoskeletal-extracellular matrix interactions. PYY induced expression of tetraspanins and intestinal fatty acid binding protein (I-FABP) may be part of a mechanism whereby FFA modulate expression of differentiation dependent proteins in the mucosa. This modulation provides a means for FFA to act as signal molecules in the feedback regulation of their own assimilation.

Full Text
Paper version not known

Talk to us

Join us for a 30 min session where you can share your feedback and ask us any queries you have

Schedule a call

Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.