Abstract
Amelanotic melanoma is an atypical melanoma that presents without pigmentation and can thus be misdiagnosed as benign neoplasm. Ungual trauma can induce amelanotic melanoma of the fingernail as well as pyogenic granuloma (PG). We present the case of a patient in his 60s with a PG-like lesion on his third nail plate that was preceded by ungual trauma one year ago. A shave biopsy revealed an ulcerated nodule composed of epitheloid cells with melanocytic atypia, extending 1.7 mm. Features were consistent with melanoma, confirmed with SOX10, S100, MART-1, and HMB45 immunostaining. This case demonstrates the integral role of histopathology and immunostaining in differentiating a benign PG from amelanotic melanoma, and thereby, preventing metastasis. We present this case to improve clinicians’ ability to recognize atypical melanomas and to emphasize the importance of biopsy in such cases to ensure timely treatment and patient outcomes.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.