Abstract
IntroductionRisk of lymph node metastases depends on good or bad prognostic features of submucosally (SM) invasive cancer specimen following endoscopic resection (ER). Invasion limited to SM1 level, lack of lymphovascular...
Highlights
This meta-analysis provides evidence that the circumferential resection margin (CRM) status in oesophageal carcinoma has prognostic significance. This significance is present irrespective of the criteria used for defining the margin but the estimate for the 0 mm CAP criterion is much higher than those of the within 1 mm RCPath criterion
The overall HR of 1.58 suggests patients with positive CRM have 60% more risk of death compared to patients with a negative margin
The status of the circumferential resection margin (CRM) in oesophageal cancer has been suggested as a prognostic factor but the reports are conflicting
Summary
The status of the circumferential resection margin (CRM) in oesophageal cancer has been suggested as a prognostic factor but the reports are conflicting. Depth of SM invasion can be very difficult to assess in ER specimens and a “safe” strategy would be to offer radical surgery to all patients with SM invasive disease, irrespective of other features. Radiotherapy may lead to dysphagia due to pharyngeal/proximal oesophageal strictures Endoscopic management of these strictures with antegrade dilation by using Savary Gilliard bougie dilators is described in literature.[1 2] Our aim was to review the outcome in patients referred for bougie dilation for radiotherapy induced strictures. The results were used to calculate their correlation with presence of glandular mucosa in BE
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