Abstract
Background Acute and Chronic Rhinosinusitis (ARS/CRS) have a strong healtheconomic impact. It can be assumed that 10-15% of the US and EU population suffers from CRS. The success of topical drug delivery to the sinuses principally desirable is limited because the paranasal cavities are virtually non-ventilated areas. An innovative inhalation system (PARI SINUS) which provides a pulsating aerosol has been shown to improve the particle deposition within the paranasal sinuses compared to an inhalation without vibration. Patients’ acceptance of this device and the clinical effects of the therapy have been evaluated.
Highlights
Acute and Chronic Rhinosinusitis (ARS/CRS) have a strong health- economic impact
The success of topical drug delivery to the sinuses principally desirable - is limited because the paranasal cavities are virtually non-ventilated areas
An innovative inhalation system (PARI SINUS) which provides a pulsating aerosol has been shown to improve the particle deposition within the paranasal sinuses compared to an inhalation without vibration
Summary
Acute and Chronic Rhinosinusitis (ARS/CRS) have a strong health- economic impact. It can be assumed that 10-15% of the US and EU population suffers from CRS. Pulsating aerosols for the rhinosinusitis treatment – evaluation of an innovative method in a multicentric survey Background Acute and Chronic Rhinosinusitis (ARS/CRS) have a strong health- economic impact. It can be assumed that 10-15% of the US and EU population suffers from CRS.
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