Pulmonary Benign Metastasizing Leiomyoma: Case Report of Late Occurrence in Postmenopausal Patient

Rafael Everton Assunção Ribeiro Da Costa,Julio Benevides Viana Neves,Cristiane Amaral Dos Reis,Lina Gomes Dos Santos

doi:10.32635/2176-9745.rbc.2022v68n1.2408

Rafael Everton Assunção Ribeiro Da Costa, Julio Benevides Viana Neves + Show 2 more

Open Access

https://doi.org/10.32635/2176-9745.rbc.2022v68n1.2408

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Abstract

Introduction: Pulmonary benign metastasizing leiomyoma (PBML) is a rare condition that occurs most commonly in young women of reproductive age some years after hysterectomy. The aim of this study was to report a PBML case which occurred 33 years after hysterectomy in a postmenopausal patient. Case report: A 59-year-old female diabetic patient, G2P2A0, with dyslipidemia, a non-smoker and ex-alcoholic (quit in the 90s), with pulmonary symptoms was referred to the health service. A chest computed tomography (CT) revealed multiple pulmonary nodules. A previous history of hysterectomy at 26 years of age led to a diagnostic hypothesis of PBML. The patient underwent segmentectomy of the largest nodule (measuring 1.2 x 0.9 cm) located in the left lung. Histopathology and immunohistochemistry studies confirmed the diagnosis of PBML. Conclusion: The patient is currently in good physical condition (regression of previous pulmonary symptoms) and scheduled for clinical follow-up. A new chest CT will be performed in 6 months.

Highlights

Pulmonary benign metastasizing leiomyoma (PBML) is a rare condition that occurs most commonly in young women of reproductive age some years after hysterectomy
The aim of this study is to report the late occurrence of PBML in a postmenopausal woman 33 years after she underwent hysterectomy
Due to the presence of multiple small nodules scattered throughout the lungs, the thoracic surgeons chose to perform segmentectomy of the largest node in the left lung in August 2021

Summary

Introduction

Pulmonary benign metastasizing leiomyoma (PBML) is a rare condition that occurs most commonly in young women of reproductive age some years after hysterectomy. The aim of this study was to report a PBML case which occurred 33 years after hysterectomy in a postmenopausal patient. The patient underwent segmentectomy of the largest nodule (measuring 1.2 x 0.9 cm) located in the left lung. Benign metastasizing leiomyoma (BLM) is a rare disorder that affects primarily the lungs and occurs most commonly in young women of reproductive age. The aim of this study is to report the late occurrence of PBML in a postmenopausal woman 33 years after she underwent hysterectomy. Due to the presence of multiple small nodules scattered throughout the lungs, the thoracic surgeons chose to perform segmentectomy of the largest node in the left lung in August 2021. The surgical specimen was sent to the laboratory for histopathology and immunohistochemistry studies (Figure 2)

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