PUK12 BURDEN OF HOSPITALIZATIONS IN UTERINE FIBROIDS (UF) PATIENTS WITH LOW AND HIGH COMORBIDITY INDEX: A PROPENSITY SCORE MATCHED ANALYSIS OF IN-PATIENT CLAIMS DATABASE

Abstract

To examine trends in morbidity, hospital length and cost of stay in UF patients with low and high comorbidity index. The latest available 2016 National Inpatient Sample (NIS) data set from the Healthcare Cost and Utilization Project was utilized in order to determine the number of hospital admissions for patients with UF. Propensity score matched analysis was conducted to compare mortality hospital, LOS and costs in patients with low and high comorbidity index. Thirty comorbidities were assessed using Elixhauser scoring. Multivariate logistic regression was conducted to assess predictor variables for LOS and costs. In 2016, there were an estimated 219,715 hospitalizations with a diagnosis of UF. Approximately 89.4% and 11.6% had comorbidity index of <4 and ≥ 4, respectively. The mean age was 42.9 (SD 10.0) and 55.5 (SD 13.8) in low and high comorbidity groups, respectively. Most common comorbidities (more than 10%) were hypertension (23.1%), chronic pulmonary disease (10.5%) and obesity (18.3%). The propensity score matched hospital LOS was 2.9 and 6.3 days, with a statistically significant difference of 3.4 days (SE 0.27, P<0.05), in low and high comorbidity groups, respectively. The propensity score matched hospital charges were $25,541 and $69,307, with a statistically significant difference of $43,766 (SE $3349, P<0.05), in low and high comorbidity groups, respectively. UF patients with high comorbidity index incur significantly longer hospital length of stay and nearly three more costs compared to patients with low comorbidity index. There is a need for better treatment management for UF patients with high comorbidity index.