Abstract
Following completion of the Drosophila genome sequence, and a full draft of the human genome, the Department of Energy's Joint Genome Institute (CA, USA) has instigated a consortium to generate a complete genome sequence for the pufferfish Fugu rubripes. Fugu has a genome that carries the same fundamental genes and regulatory sequences as in humans, but is one-eighth of the size. This is due in part to the massive reduction in the size and number of introns. Comparative genomics using mouse sequence have proved extremely fruitful in decoding the human sequence, and it is hoped that researchers will elicit similarly valuable information from the pufferfish sequence. The consortium includes research groups from Los Alamos (CA), Pacific Northwest (WA) and Brookhaven (NY) National Laboratories, and Stanford University (CA). (AR)
Published Version
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