PTU-155 Investigation of the relationship between age, gender, body mass index (BMI) and bone mineral density (BMD) as assessed by dual-energy x-ray absorptiometry (DXA) of the spine and left femur in newly diagnosed patients with coeliac disease (CD)

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Introduction CD is a risk factor for osteoporosis and low BMD (osteopenia). Present national guidelines (BSG 2007) do not identify young patients with CD as being at risk of low BMD. Few studies have investigated BMD in coeliac patients below 40 years of age. This audit analysed the DXA results of newly diagnosed coeliac patients attending a coeliac clinic. Method BMD (age matched Z-scores) as assessed by DXA in consecutive patients with CD between 2013 and 2014 were compared for age, gender and BMI (majority ≤12 months of diagnosis). Low BMD was defined locally as: Z-score -1.5. This compares to WHO criteria for osteopenia: T-score of -2.5 and osteoporosis: T-score of ≤-2.5. Results Conclusion Current UK guidelines (BSG 2007) recommend that BMD should be measured in coeliac patients after 1 year of a gluten-free diet (GFD) in patients who have additional risk factors for osteoporosis or if over 55 years. We found 28% of patients Disclosure of interest None Declared. Reference British Society of Gastroenterology (BSG). Guidelines for osteoporosis in inflammatory bowel disease and coeliac disease, 2007