Abstract

Objective To analyze the effect of pterygium excision combined with autologous limbal stem cell transplantation for patients with pterygium. Methods 42 pterygium patients (66 eyes) treated at our hospital from March, 2015 to May, 2016 were included into the study; Using random number table method, they were divided into a control group and an observation group, 33 eyes for each group. The control group were treated with pterygium excision and the observation group with pterygium excision and autolgous corneal limbal stem cell transplantation. Both groups were followed by 6 months. Results After the surgery, the uncorrected visual acuity was higher in the observation group than in the control group [(0.83±0.15) vs. (0.73±0.15)]. The corneal epithelial repair time and stitches-off time were shorter in the observation group than in the control group [(2.12±0.68) d vs. (2.67±0.96) d and (4.97±0.81) d vs. (5.70±0.92) d], with statistical differences (both P<0.05). After the treatment, the cured rate was higher in the observation group than in the control group (93.94% vs. 75.76%) , with a statistical differences (P<0.01). Conclusion Pterygium excision combined with limbal stem cell translations has good overall effect and can improve the pterygium corneal astigmatism and vision. Key words: Pterygium excision; Limbal stem cell transplantation; Pterygium; Clinical effect

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