Effects of two methods for primary pterygium on corneal epithelial repairment and recurernce rate

Abstract

Objective To compare the clinical effects of Pterygium excision and autologous corneal limbal stem cell tran splantation combined with pterygium excision on primary pterygium. Methods Eighty-three patients（92 eyes） with primary pterygium were chose,41 patients（46 eyes）in group A were given simple pterygium excision,with MMC used during the operation,42 patients（46 eyes）in group B were given autologous corneal limbal stem cell transplantation combined with pterygium excision. The post-operative follow-up periods ranged from 6-12 months. The corneal wouds healing,corneal astigmia and the recurrent rate of the two groups were compared. Results The average corneal wouds healing time was 7. 34 d in group A and 6. 32 d in group B,there was significant difference between the two groups（ P﹤0. 05 ）. There was no significant difference in the corneal astigmia degree between the two groups at 3 months after operation（ P﹥0. 05）. The recurrent rate was 17. 4%（8 eyes）in group A and 4. 3%（2 eyes）in group B,there was significant difference between the two groups（ P﹤0. 05 ）. Conclusions The method of pterygium excision combined with autologous corneal limbal stem cell transplantation is superior to single pterygium excision. Key words: Pterygium ; Corneal limbal stem cell transplantation ; Mitomycin C （ MMC ）