Abstract
Chronic open-angle glaucoma is recognized by a disturbance of visual function and optic nerve changes. Localized visual field defects, indicative of damage to nerve fiber bundles, are usually preceded by changes of the optic nerve head and the retinal nerve fiber layer (RNFL). Airaksinen et als observed the sequential appearance of disc hemorrhages, RNFL abnormalities, changes in the neuroretinal rim and, finally, nerve fiber bundle damage and visual field defects in glaucoma patients. Pederson and Anderson” also reported that generalized enlargement of the optic cup occurs prior to visual field defects. Sommer,14 however, found that at least 12% of the glaucoma suspects who subsequently developed a visual field defect had a clinically normal neuroretinal rim. In these patients, there was no photographic evidence of a change in cup size prior to the development of the visual defect. These findings were confirmed by Motolko et allo
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