Abstract

The correlation between psychopathological disorders and indicators related to the effector molecule in cell-mediated immunity in HIV-infected patients with schizophrenia and schizoaffective disorder has been studied using comparison of means and regression analysis. HIV infection affects individual indicators of the effector molecule in cellular immunity in patients with paranoid schizophrenia and schizoaffective disorder, and its influence differs in schizophrenia and schizoaffective disorder and in various forms of schizophrenia. The structure of psychopathological disorders in HIV-infected patients with schizophrenia and schizoaffective disorder correlates with the immunoregulatory index CD4+/CD8+, which reflects the involvement of the effector of cell-mediated immunity in the formation of a clinical picture of psychopathological disorders.

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