Abstract

BackgroundPatients with lower extremity problems (LEP) commonly experience functional loss, pain, decreased range of motion, inadequacy in daily living activities, and structural change in radiographic evaluations. However, the traditional patient-reported outcome measurement which focused on symptoms, had a limited scope of applicability. This study aimed to validate the psychometric properties of the Korean version of PROMIS-29 Profile v2.1 (K-PROMIS-29 V2.1), a multi-dimensional measure for assessing generic profile health-related quality-of-life (HRQoL) in a sample of patients with lower extremity problems (LEP).MethodsParticipants were recruited from the orthopedic outpatient clinics at the Samsung Medical Center in Seoul, South Korea from September to October 2018. Participants completed a survey questionnaire that included the K-PROMIS-29 V2.1 and the SF-36v2. Principal component analysis (PCA) and confirmatory factor analysis (CFA) and Pearson’s correlations were used to evaluate the reliability and validity of the K-PROMIS-29 V2.1.ResultsA total of 299 participants were enrolled in the study and 258 (86%) completed the study questionnaire. The mean age (SD) of the participants was 56.6 (14.5) and 32.3%, 29.8, and 25.2% of the study participants visited outpatient clinics for foot, knee, and hip problems respectively. The Cronbach’s alpha coefficients of 7 sub-domains in K-PROMIS-29 V2.1 ranged from 0.80 to 0.95, indicating satisfactory internal consistency. In CFA, the goodness-of-fit indices were high (CFI = 0.937 and SRMR = 0.061). High to moderate correlations were found between comparable subscales of the K-PROMIS-29 V2.1 and subscales of the SF-36v2 (r = 0.55–0.70).ConclusionsThe K-PROMIS-29 V2.1 is a reliable and valid measure for assessing a broad range of health-related quality-of-life domains in patients with LEP. It would reflect the real-life symptoms experienced by patients with LEP.

Highlights

  • Patients with lower extremity problems (LEP) commonly experience functional loss, pain, decreased range of motion, inadequacy in daily living activities, and structural change in radiographic evaluations

  • Regarding the ability to participate in social roles and activities in K-Patient-Reported Outcomes Measurement Information System (PROMIS)-29 V2.1, there were moderate correlations observed with role-physical (r = 0.60), social functioning (r = 0.55), and role-emotional (r = 0.54) in Short Form Health Survey ver‐ sion-2.0 (SF-36v2)

  • This study adds to the evidence base supporting the reliability and validity of K-PROMIS-29 V2.1 in assessing quality of life among Korean speakers being treated for lower extremity problems

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Summary

Introduction

Patients with lower extremity problems (LEP) commonly experience functional loss, pain, decreased range of motion, inadequacy in daily living activities, and structural change in radiographic evaluations. The traditional patient-reported outcome measurement which focused on symptoms, had a limited scope of appli‐ cability. This study aimed to validate the psychometric properties of the Korean version of PROMIS-29 Profile v2.1 (K-PROMIS-29 V2.1), a multi-dimensional measure for assessing generic profile health-related quality-of-life (HRQoL) in a sample of patients with lower extremity problems (LEP). Kim et al BMC Sports Science, Medicine and Rehabilitation (2021) 13:148 and patient-reported outcome measures (PROMs). LEP patients often experience functional loss, pain, decreased range of motion, inadequacy in daily living activities [4,5,6]. A thorough assessment of the utility of treatment for LEP should be more comprehensive than the approach we have applied in the past to other conditions, and requires the application of a meaningful, appropriate PROMs [7, 8]

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