Abstract
Purpose: Chronic liver disease (CLD) is a major public health problem worldwide and it leads to increase in morbidity and mortality. This study aimed to evaluate the psychometric properties of Chronic Liver Disease Questionnaire (CLDQ) in Turkish patients with Chronic liver disease (CLD).
 Material and Methods: The study was conducted in the methodological research design. Using a convenience sampling method 235 patients with CLD in a university hospital, located in southern Turkey. The instrument’s psychometric properties were examined to determine factor analysis, criterion-related validity, internal consistency, interrater reliability.
 Results: The patients average age was 55.48±12.02 years. Viral hepatitis was the most common etiology of CLD (53.6%). The total sample had a mean CLDQ score of 4.73±1.12. 
 The factor analysis revealed that the scale consists of six sub-dimensions. No item was removed from the original scale. Cronbach's alpha coefficient was found as 0.95. 
 Conclusion: Valid and reliable measurement tools are needed to evaluate health related quality of life (HRQoL) in patients with liver disease. Chronic Liver Disease Questionnaire is a valid and reliable measurement instrument.
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